Excitation-Neurogenesis Coupling in Adult Neural Stem/Progenitor Cells

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Excitation-Neurogenesis Coupling in Adult Neural Stem/Progenitor Cells

A wide variety of in vivo manipulations influence neurogenesis in the adult hippocampus. It is not known, however, if adult neural stem/progenitor cells (NPCs) can intrinsically sense excitatory neural activity and thereby implement a direct coupling between excitation and neurogenesis. Moreover, the theoretical significance of activity-dependent neurogenesis in hippocampal-type memory processi...

متن کامل

GABA Excitation in the Adult Brain: A Mechanism for Excitation- Neurogenesis Coupling

The production of new neurons in the adult hippocampus is exquisitely regulated, and alterations in this process may underlie both normal and pathological hippocampal function. In this issue of Neuron, Tozuka et al. describe electrophysiological recordings that target proliferating progenitor cells in adult mouse hippocampal slices. They report that GABAergic synaptic inputs directly depolarize...

متن کامل

Alcohol, neural stem cells, and adult neurogenesis.

Recent research demonstrates that neural stem cells divide throughout life and give rise to new neurons, a process known as neurogenesis. This article addresses two principal questions concerning alcohol and adult neurogenesis: To what extent are neurogenesis in the adult brain and the risk for alcoholism governed by similar factors? And, to what extent and through what mechanisms do alcohol us...

متن کامل

Neurogenesis in embryos and in adult neural stem cells.

How the differentiated cell types that comprise the vertebrate CNS are generated during development is one of the central questions in developmental neurobiology. Considerable progress recently made in addressing this question has led to a rudimentary understanding of the molecular mechanisms that enable cells to acquire a neural fate in embryos. The purpose of this review is to discuss how the...

متن کامل

Neural stem cells and neurogenesis in the adult.

Research in the field of adult neurogenesis has seen substantial progress over recent years. Here we discuss some of the major focus areas for future investigation: neural stem cell heterogeneity, the role of latent stem cells, and the extent of neurogenesis in the adult human brain.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Neuron

سال: 2004

ISSN: 0896-6273

DOI: 10.1016/s0896-6273(04)00266-1